Immune checkpoint drugs have transformed cancer care, but most patients still don't respond. A sweeping new review in Cell Metabolism argues the gut microbiome is a central reason why, and a potential lever to change that.
The bacteria living in your gut are not passive passengers. A sweeping new review finds they actively shape your blood pressure by churning out metabolites that reach your arteries, immune cells, and hormonal systems.
Eating more oats and chicory-derived fibers could do more than support digestion. A new study of people genetically predisposed to Crohn's disease links beta-glucan and inulin intake to meaningful protection against developing the condition.
What started as a last-resort treatment for stubborn gut infections is quietly becoming one of medicine's most ambitious biotechnology platforms. A sweeping new review maps how fecal microbiota transplantation is shedding its "black box" reputation on the way to precision therapy.
A new study tracks exactly how the infant gut transitions from breast milk to solid food, and the bacteria that thrive are the ones that can digest both at once.
Researchers have grown centimeter-scale human gut tissue that spontaneously wires itself with a functional nervous system, cutting the maturation timeline in half and surviving transplantation into living rodents.
When surgeons operate on the colon or rectum, they don't just cut tissue - they throw the entire gut microbial ecosystem into chaos. A new study reveals that bacteria and fungi recover from that disruption on very different timelines, and the gap between them could shape how patients heal.
Scientists now have strong evidence that specific gut bacteria do not just tag along with colorectal cancer; they help cause it. A sweeping new review maps the molecular mechanisms and points toward therapies that could one day exploit the microbiome against tumors.
A clinical trial analysis reveals that ramping up fiber intake to 50 grams a day remodels the gut's bile acid chemistry in melanoma patients on immunotherapy, and mouse experiments suggest that chemical shift is part of why the diet works.
Researchers tracked gut microbiome changes in 335 remote Amazonian Indigenous people over four months of routine medical treatment, and found that diversity collapsed quickly, even without dietary or lifestyle changes.