A large Chinese cohort study found that gastrointestinal disease and heart disease each predict the other's onset years later, with depression explaining part of the link in both directions.
A systematic review of 12 randomized trials found multistrain probiotics roughly halved the odds of chemotherapy-related diarrhea in colorectal cancer patients, though the evidence base is still small and heterogeneous.
A new study of 200 adults found that specific gut and mouth bacteria species, along with two fecal metabolites, correlate with scores on a standard psychopathic-personality-traits scale. The link is the first of its kind, small in size, and strictly correlational.
A review in iNew Medicine proposes that high-sugar diets disrupt gut bacteria, barrier, immunity and metabolism through one shared pathway, helping explain the parallel rise of inflammatory bowel disease, food allergy and colorectal cancer, though the human evidence remains observational.
A compound made by common gut bacteria, indole, appears to prime the immune system for more severe brain damage after a stroke, a new study in mice and stroke patients finds. Blocking the pathway protected mice from injury, pointing to gut bacteria as a stroke-severity factor worth further research.
A new study ties oxalate, a compound in virtually all plant foods, to reduced gut transporter activity in IBD patients and worsened colitis in mice, though human causation remains unproven.
A newly updated systematic review of nine human intervention studies (517 participants) found no consistent effect of time-restricted eating on gut microbiota diversity in adults with overweight or obesity. Three of five randomized trials saw no change, and the overall certainty of the evidence was rated very low.
A new modeling study links two gut bacteria species, Bacteroides uniformis and Bacteroides thetaiotaomicron, to blood chemistry changes already tied to Alzheimer's disease, with the effect shaped by a person's APOE gene. The predictions did not fully match real blood test results, so the authors call it a hypothesis to test further, not a diagnosis or treatment.
A five-year study of hospitalized cancer patients found that eating more sweets while on antibiotics tracked with steeper gut bacterial diversity loss and overgrowth of a harmful bacterium, a pattern mouse experiments helped confirm.
A new study finds that children with autism and non-autistic children carry similar gut bacteria, but those bacteria produce a chemically different, more inflammatory toxin, one that triggers a stronger reaction in human brain immune cells in lab tests.
